Metformin Treatment of Type 2 Diabetes Mellitus in Pregnancy: Update on Safety and Efficacy Publication Metformin Treatment of Type 2 Diabetes Mellitus in Pregnancy: Update on Safety and Efficacy CertaraApril 25, 2018
Clarification of Contraceptive Drug Pharmacokinetics in Obesity Publication Clarification of Contraceptive Drug Pharmacokinetics in Obesity CertaraJanuary 1, 2017
Study Reanalysis Using a Mechanism-based Pharmacokinetic/Pharmacodynamic Model of Pramlintide in Subjects with Type 1 Diabetes Publication Study Reanalysis Using a Mechanism-based Pharmacokinetic/Pharmacodynamic Model of Pramlintide in Subjects with Type 1 Diabetes This report describes a pharmacokinetic/pharmacodynamic model for pramlintide, an amylinomimetic, in type 1 diabetes mellitus…CertaraJanuary 1, 2015
Population Pharmacokinetic Analysis of Dutogliptin, a Selective Dipeptidyl Peptidase-4 Inhibitor Publication Population Pharmacokinetic Analysis of Dutogliptin, a Selective Dipeptidyl Peptidase-4 Inhibitor Dutogliptin is a selective dipeptidyl peptidase-4 inhibitor shown to be efficacious and safe in patients…CertaraJuly 14, 2014
Pharmacometric Approaches to Guide Dose Selection of the Novel GPR40 Agonist TAK-875 in Subjects with Type 2 Diabetes Mellitus Publication Pharmacometric Approaches to Guide Dose Selection of the Novel GPR40 Agonist TAK-875 in Subjects with Type 2 Diabetes Mellitus The G-protein-coupled receptor 40 agonist (GPR40) TAK-875 is being developed as an adjunct to diet…CertaraJanuary 9, 2013
Population Pharmacokinetic Model for a Novel Oral Hypoglycemic Formed In Vivo: Comparing the Use of Active Metabolite Data Alone Versus Using Data of Upstream and Downstream Metabolites Publication Population Pharmacokinetic Model for a Novel Oral Hypoglycemic Formed In Vivo: Comparing the Use of Active Metabolite Data Alone Versus Using Data of Upstream and Downstream Metabolites The purpose of this analysis was to develop a population pharmacokinetic model for CS-917, an…CertaraMarch 1, 2012
The Use of Biosimulation in the Design of a Novel Multilevel Weight Loss Maintenance Program for Overweight Children Publication The Use of Biosimulation in the Design of a Novel Multilevel Weight Loss Maintenance Program for Overweight Children Weight loss outcomes achieved through conventional behavior change interventions are prone to deterioration over time.…CertaraFebruary 18, 2010
CYP2D6 is Primarily Responsible for the Metabolism of Clomiphene Publication CYP2D6 is Primarily Responsible for the Metabolism of Clomiphene Clomiphene is a first line treatment for anovulation, a common cause of infertility. Response to…CertaraApril 30, 2008