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What are clinical trial outcomes databases? How and why you should use them.

Publicly available clinical trial data represents an underutilized source of information. If properly extracted and analyzed, they provide valuable information to support drug development decisions. When you think of the volumes of public information and databases that are available to determine, for example, commercial viability of a therapeutic in development, your first inclination is—“great!” But … Continued

Quantify Osteoarthritis Pain Clinical Outcomes Database

The current version of the database includes clinical safety and efficacy information on treatment options currently approved or in development for osteoarthritis pain. The current version of the database includes information on all systemic pharmacological interventions. This includes mono and combination therapy with NSAIDs, acetaminophen, opioids, COX-2 inhibitors, norepinephrine reuptake inhibitors, anti-NGF, anti-epileptic drugs (AEDs), antidepressants, and muscle relaxants.

CODEx Orthopedic Surgery Clinical Outcomes Database

The Quantify Thrombosis in Orthopedic Surgery (TOS) Clinical Outcomes Database contains bleeding and VTE endpoint data from clinical trials investigating pharmaceutical interventions for preventing peri-operative thrombosis after orthopedic surgery of hip, knee, or both.

Quantify HBV Clinical Outcomes Database

The Quantify HBV Database is developed to document clinical safety and efficacy information on different nucleosides (eg, entecavir, lamivudine, tenofovir disoproxil fumarate, telbivudine, adefovir and combination) focusing on 3 different endpoints: HBV DNA time course, HBsAG time course, and HBeAG seroconversion that are available in the public domain.

Quantify Chronic Lower Back Pain Clinical Outcomes Database

The current version of the database includes clinical safety and efficacy information on treatment options currently approved or in development for chronic lower back pain. The current version of the database includes information on all systemic pharmacological interventions. This includes mono and combination therapy with NSAIDs, acetaminophen, opioids, COX-2 inhibitors, norepinephrine reuptake inhibitors, anti-NGF, anti-epileptic drugs (AEDs), antidepressants, and muscle relaxants.

Quantify Multiple Sclerosis Clinical Outcomes Database

The current version of the database includes clinical safety and efficacy information on disease modifying therapies that are on the market or late stage clinical development for relapsing, remitting, and secondary progressive multiple sclerosis.

Quantify Neuropathic Pain Clinical Outcomes Database

The current version of the database includes clinical safety and efficacy information on treatment options currently approved or in development for painful diabetic neuropathy (DPN), post herpetic neuralgia (PHN), or fibromyalgia. Information on older treatment options (such as tricyclic antidepressants) was included if they are used as active controls.

Quantify IPF Clinical Outcomes Database

The Quantify IPF Clinical Outcomes Database contains data from randomized clinical trials assessing pharmacological interventions for treatment of idiopathic pulmonary fibrosis.

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