Biologics Archives

Poster

Optimizing Avidity of Bispecific Drugs

Abstract Bispecific drugs have great potential to improve tissue selectivity through avid binding interactions but…

CertaraSeptember 9, 2024

Poster

Effects of Tissue Targeting Bispecifics on Therapeutic Window

Abstract Objectives: The presence of target receptors in non-target tissues can reduce the therapeutic window…

CertaraSeptember 9, 2024

Case Study

Optimizing Clinical Development: Saving Time and Costs

Strategic mechanistic modeling solutions help an immunoncology biotech accelerate their clinical development of novel therapeutics.

CertaraAugust 16, 2024

Publication

Application of Quantitative Systems Pharmacology to guide the optimal dosing of COVID-19 vaccines

Optimal use and distribution of coronavirus disease 2019 (COVID-19) vaccines involves adjustments of dosing. Due…

CertaraJuly 31, 2021

Blog

Maximizing Oligonucleotide Therapeutic Development: How They Work

This is the first of three blog posts discussing best practices for developing oligonucleotides. Interest…

CertaraMay 7, 2021

On-Demand Webinar

The Promises and Pitfalls of Gene Therapy for Rare Diseases

The state of gene therapy faces much uncertainty as recent regulatory and clinical setbacks have…

CertaraApril 29, 2021

Blog

Getting Gene Therapies to Patients

This blog discusses the challenges that drug developers face in getting patients access to cell…

CertaraFebruary 16, 2021

Case Study

Early Value Assessment in Gene Therapy Clinical Trial Design

A global biotechnology company engineering precision genetic medicine for rare diseases was in need of…

CertaraFebruary 12, 2021

Blog

8 Tips for Successfully Developing Oligonucleotide Therapies

By Eva Gil Berglund and Nathalie H Gosselin Oligonucleotide therapeutics are a validated class of…

CertaraFebruary 1, 2021

Biologics

Optimizing Avidity of Bispecific Drugs

Effects of Tissue Targeting Bispecifics on Therapeutic Window

Optimizing Clinical Development: Saving Time and Costs

Application of Quantitative Systems Pharmacology to guide the optimal dosing of COVID-19 vaccines

Maximizing Oligonucleotide Therapeutic Development: How They Work

The Promises and Pitfalls of Gene Therapy for Rare Diseases

Getting Gene Therapies to Patients

Early Value Assessment in Gene Therapy Clinical Trial Design

8 Tips for Successfully Developing Oligonucleotide Therapies

Newsletter sign up

Quick links

Solutions

Contact