Applications of Linking PBPK and PD Models to Predict the Impact of Genotypic Variability, Formulation Differences, Differences in Target Binding Capacity and Target Site Drug Concentrations on Drug Responses and Variability

Author(s): Manoranjenni Chetty, Rachel Rose, Khaled Abduljalil, Nikunjkumar Patel, Gaohua Lu, Theresa Cain, Masoud Jamei, Amin Rostami-Hodjegan
Year: November 26, 2014