In this pharmacokinetic/pharmacodynamic meta-analysis, we investigated relationships between clinical endpoints and sunitinib exposure in patients with advanced solid tumors, including patients with gastrointestinal stromal tumor (GIST) and metastatic renal cell carcinoma (mRCC).
Author(s): Brett Houk, Carlo Bello, Bill Poland, Lee Rosen, George Demetri, Robert Motzer
Year: July 1, 2010