Population Pharmacokinetics and Bayesian Estimation of Tacrolimus Exposure in Pediatric Liver Transplant Recipients

Objectives of this study were to develop a population pharmacokinetic (PopPK) model for tacrolimus in pediatric liver transplant patients and determine optimal sampling strategies (OSS) to accurately estimate tacrolimus exposure.

Author(s): Nastya Kassir, Line Labbé, Jean‐Romain Delaloye, Mohamad-Samer Mouksassi, Anne-Laure Lapeyraque, Fernando Alvarez, Michel Lallier, Mona Beaunoyer, Yves Théorêt, Catherine Litalien

Year: June 1, 2014