Quantitative systems pharmacology (QSP) models generate predictions by formalizing biological understanding and integrating multiscale data, leading to beneficial extrapolation abilities, but may require careful balancing of the model’s scope with prediction uncertainties.
Author(s): Vincent Lemaire, Chuanpu Hu, Piet H. van der Graaf, Steve Chang, Weirong Wang
Year: November 9, 2023