A Tutorial on Pharmacodynamic Scripting Facility in Simcyp

The Simcyp® Simulator provides a framework for mechanistic Physiologically-Based Pharmacokinetic/Pharmacodynamic modelling of potentially interacting drugs. It also provides a scripting facility, using the Lua language, for developing customised pharmacodynamic and toxicity models driven by drug concentrations at the site of action.

Author(s): Khaled Abduljalil, Duncan Edwards, Adrian Barnett, Rachel Rose, Theresa Cain, Masoud Jamei

Year: July 9, 2016