Historically, vaccine development and dose optimization have followed mostly empirical approaches without clinical pharmacology and model-informed approaches playing a major role, in contrast to conventional drug development. This is attributed to the complex cascade of immunobiological mechanisms associated with …
A quantitative clinical pharmacology-based framework for model-informed vaccine development
November 20, 2023
Author(s): Rajat Desikan,Massimiliano Germani, Piet H. van der Graaf, Mindy Magee
Year: November 2, 2023