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Visit careers siteHome / Publication / A Literature Review of Changes in Phase II Drug-Metabolizing Enzyme and Drug Transporter Expression during Pregnancy
This comprehensive review exposes gaps in current knowledge of phase II enzyme and drug transporter localization, expression, and regulation during pregnancy, which emphasizes the need for further research. The information collected will aid in optimizing pregnancy PBPK models to inform dose selection in pregnancy population.
Author(s): Christine Gong, Lynn N. Bertagnolli, David W. Boulton, Paola Coppola
Year: November 15, 2023
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