A Distributed Delay Approach for Modeling Delayed Outcomes in Pharmacokinetics and Pharmacodynamics Studies

Author(s): Shuhua Hu, Kevin Feng, Bob Leary, Mike Dunlavey

This poster demonstrates that the distributed delay approach is general enough to incorporate a wide array of models as special cases including transit compartment models, typical absorption models, and models for describing atypical absorption profiles such as double/multiple-peak phenomenon after oral administration in pharmacokinetics.