Page 55 | Certara

Publication

Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a recombinant human monoclonal antibody

The article titled "Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a…

CertaraNovember 4, 2024

Conference

JSCPT 2025

–

CertaraOctober 31, 2024

Case Study

Clinical Candidate Selection

In this case study, we look at an example of targeting a membrane bound protein…

CertaraOctober 31, 2024

Case Study

Phase 1 Interim Analysis

In this case study, we continue to work with the model and analysis from Immuno-modulation…

CertaraOctober 31, 2024

On-Demand Webinar

Improved Translation of Clinical TCE Dosing with Mechanistic Modeling

Abstract: Regulatory agencies recommend quantitative justifications for clinical dose selection. T-cell engagers (TCE) pose particular…

CertaraOctober 31, 2024

On-Demand Webinar

Applications of a QSP Model of LNP mRNA Delivery for the Treatment of Crigler-Najjar Syndrome Type 1

Abstract: Crigler-Najjar syndrome type 1 (CN1) is an autosomal recessive disease caused by a marked…

CertaraOctober 31, 2024

On-Demand Webinar

Guiding Target and Lead Optimization for a Molecular Glue Degrader

Learn how to optimize drug properties for protein degrader therapeutics by exploring system characteristics.

CertaraOctober 31, 2024

On-Demand Webinar

Capturing CAR T-cell Therapy Dynamics Through Mechanistic Modeling

Abstract: Chimeric antigen receptor T (CAR T)-cell therapy has shown remarkable success in treating various…

CertaraOctober 31, 2024

On-Demand Webinar

Physiologically Based Pharmacokinetic Modelling, an Integrative Approach to First in Human (FIH) Studies [APAC Webinar]

Physiologically Based Pharmacokinetic (PBPK) modelling is an integrative approach facilitating the optimal use of various…

CertaraOctober 31, 2024

Video

Part 5: Regulatory Outlook on Data Management

In this video interview with ACT editor Andy Studna, Erin Erginer, director of product, Certara…

CertaraOctober 31, 2024

Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a recombinant human monoclonal antibody

JSCPT 2025

Clinical Candidate Selection

Phase 1 Interim Analysis

Improved Translation of Clinical TCE Dosing with Mechanistic Modeling

Applications of a QSP Model of LNP mRNA Delivery for the Treatment of Crigler-Najjar Syndrome Type 1

Guiding Target and Lead Optimization for a Molecular Glue Degrader

Capturing CAR T-cell Therapy Dynamics Through Mechanistic Modeling

Physiologically Based Pharmacokinetic Modelling, an Integrative Approach to First in Human (FIH) Studies [APAC Webinar]

Part 5: Regulatory Outlook on Data Management

Newsletter sign up

Quick links

Solutions

Contact