Prediction of mAb disposition in hepatic impairment – Evolocumab as a case study Poster Prediction of mAb disposition in hepatic impairment – Evolocumab as a case study CertaraOctober 15, 2019
Use of a physiologically based pharmacokinetic – pharmacodynamic (PBPK-PD) model to guide dose adjustments to S-warfarin in different populations Poster Use of a physiologically based pharmacokinetic – pharmacodynamic (PBPK-PD) model to guide dose adjustments to S-warfarin in different populations CertaraOctober 15, 2019
Biopharmaceutic In Vitro In Vivo Extrapolation (IVIV_E) Informed PBPK Model of Ritonavir Norvir® Tablet Absorption in Humans Under Fasted and Fed State Conditions Poster Biopharmaceutic In Vitro In Vivo Extrapolation (IVIV_E) Informed PBPK Model of Ritonavir Norvir® Tablet Absorption in Humans Under Fasted and Fed State Conditions CertaraOctober 15, 2019
Accounting for CYP2C19 mechanism based inhibition and CYP1A2 induction in a PBPK model for omeprazole Poster Accounting for CYP2C19 mechanism based inhibition and CYP1A2 induction in a PBPK model for omeprazole CertaraOctober 11, 2019
Physiological verification of a geriatric population using the Simcyp R package Poster Physiological verification of a geriatric population using the Simcyp R package CertaraOctober 11, 2019
Estimation of Effective pKa of Bicarbonate Buffer Poster Estimation of Effective pKa of Bicarbonate Buffer CertaraOctober 11, 2019
Quantification of Human Blood-Brain Barrier Transporters in Health and in Dementia by Global and Targeted Proteomics Poster Quantification of Human Blood-Brain Barrier Transporters in Health and in Dementia by Global and Targeted Proteomics CertaraOctober 11, 2019
The Molecular Stethoscope: RNA of Drug Metabolising Enzymes in Circulating Vesicles Correlates with their Specific Protein Content in the Liver Poster The Molecular Stethoscope: RNA of Drug Metabolising Enzymes in Circulating Vesicles Correlates with their Specific Protein Content in the Liver CertaraOctober 11, 2019
Propofol: A Tail of Drug Disposition and Dynamics in Different Dog Breeds Poster Propofol: A Tail of Drug Disposition and Dynamics in Different Dog Breeds CertaraOctober 11, 2019
Health Canada PRCI Guiding Principles and Observations Blog Health Canada PRCI Guiding Principles and Observations Health Canada released guidance on March 12, 2019 pertaining to its Public Release of Clinical…CertaraSeptember 16, 2019