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Date: Thursday, April 10, 2025

Time: 9am – 5pm ET

Location: Le Meridien Boston Cambridge, 20 Sidney Street, Cambridge, MA 02139

Summary

The Quantitative Systems Pharmacology (QSP) Summit is a free conference dedicated to fostering an active community of industry and academic participants interested in topics relevant to QSP. In its eighth year, the QSP Summit is a one-day event featuring talks from key industry and academic researchers and networking time with peers.

Speakers:

Panelists:

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Agenda

9:00 AM – 9:30 AM
Breakfast and Registration
9:30 AM – 9:45 AM
Opening remarks

Joshua Apgar, VP, Head of QSP Software, Certara

9:45 AM – 10:20 AM
QSP at Scale: Unlocking New Frontiers in Predictive Modeling

Piet van der Graaf, PharmD, PhD, FBPhS, Senior Vice President and Head of Quantitative Systems Pharmacology, Certara

10:20 AM – 10:55 AM
Application of Physiologically Based PK (PBPK) modeling in LNP based mRNA therapeutics

Hojjat Bazzazi, Director, Quantitative System Pharmacology, Moderna Therapeutics

10:55 AM – 11:25 AM
Break
11:25 AM – 12:00 PM
Modeling targeted protein degradation from cells to the clinic

Allison Claas, Sr Principal Scientist, Novartis

12:00 PM – 12:35 PM
Beyond Bispecifics: Using Quantitative Systems Pharmacology to Strategically Develop Tetraspecific T Lymphocyte Activation and Survival Enhancement Receptor (LASER) Abs for Solid Tumors

Kerry Culm, Chief Development Officer, ModeX Therapeutics

12:35 PM – 1:35 PM
Lunch
1:35 PM – 2:10 PM
QSP has come of age, now how do we scale?: A sneak peak at Certara IQ

Joshua Apgar, VP, Head of QSP Software, Certara

2:10 PM – 2:45 PM
Past, Present and Future Through the Lens of QSP and QST

Anna Sher, Sr Director, QSP, GSK

10:55 AM – 11:25 AM
Break
3:15 PM – 3:50 PM
Using Virtual Patients to Evaluate Dosing Strategies for Bispecifics with a Bell-Shaped Efficacy Curve

Irina Kareva, Associate Director, Quantitative Pharmacology, EMD Serono

3:50 PM – 4:50 PM
Panel Discussion

Panelists:

  • John M. Burke, Chief Pharmacology Officer – Fractional, Reverb Therapeutics
  • Karthik Venkatakrishnan, Vice President and Global Head of Quantitative Pharmacology, EMD Serono
  • Haojing Rong, Chief Development Officer, Stealth NewCo, Atlas Ventures
4:50 PM – 5:00 PM
Closing Remarks and Conclusion of the QSP Summit

Piet van der Graaf

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