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PK/PD Data Analysis, Concepts and Applications eBook 

Learn & grow with the standard book for PK scientists

Certara is proud to offer a golden opportunity for learners and experts in pharmacokinetics & pharmacodynamics! The standard book is available FREE of charge!

Why is this book a must-have?

🏆 A trusted resource for generations of PK experts.

💡 Comprehensive insights into both theory and practice of PK/PD.

🤝 Authored by distinguished experts in the field.

Simply add your email address & you’ll be sent an email to create an account and gain access to the eBook, as well as a wide range of additional educational resources.

Please use your professional or academic email for registration, as personal email accounts (e.g., Gmail) are not accepted. If your organization hasn’t been a recent Certara customer, approval of your account may take several business days.

Master PK/PD analysis with expert tutorials

Through numerous examples and over 100 tutorials, scientists learn how to apply PK/PD analysis in a variety of practical areas, from simple plasma kinetics, multi-compartment models, nonlinear kinetics, plasma protein binding, pharmacodynamic models, turnover concepts, receptor binding, functional adaptation and rebound, dose-response-time data analysis, inter-species scaling, target mediated drug disposition, and a lot more.

Simply fill out the form to gain exclusive access to Pharmacokinetic and Pharmacodynamic Data Analysis, PK/PD Concepts and Applications, 5th edition.

Be prepared to embark on a transformative learning experience that will shape your future!

What you'll find in the eBook

Chapter 1

  • Basic Concepts

Chapter 2

  • Intravenous Bolus Administration
  • Absorption Parameters
  • Plasma and Urine Data
  • Extravascular administration
  • Turnover
  • Nonlinear Systems
  • Non-Compartmental Analysis
  • Exposure
  • Inter-Species Scaling

Chapter 3

  • Receptor Binding Models
  • Pharmacodynamic Models
  • Antagonism
  • Reversible Drug Effects
  • Irreversible Drug Effects
  • Effect Compartment (Link) Models
  • Dose-Response-Time Models
  • Tolerance and Rebound Models
  • Baseline Models
  • Transduction Models
  • Synergistic Effects

Chapter 4

  • Plot and Explore Data
  • Graphical methods and linear Regression
  • Assessing the Goodness-of-Fit
  • F Test
  • Akaike and Schwarz criteria
  • Outliers

Chapter 5

  • Experimental Design

Chapter 6

  • Pattern Recognition
  • Pharmacokinetic Applications
  • One-compartment
  • Two-compartment
  • Bolus
  • Toxicokinetics
  • Ethanol kinetics
  • Metabolite kinetics
  • Nonlinear Kinetics
  • Allometry
  • In vitro/in vivo extrapolation
  • Constant K
  • Michaelis-Menten Kinetics
  • r-hSOD kinetics

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"This book raises the stature of PK/PD modeling to its highest level"

European Journal of Pharmaceutical Sciences