Radiometric Analysis
One of the oldest methods used for the quantitation of drug molecules is radiometric analysis.…
CertaraJuly 29, 2014
Understanding LC/MS/MS
The most common bioanalytical method in use today is LC/MS/MS, or liquid chromatography (LC) tandem…
CertaraJuly 15, 2014
What is HPLC/UV?
In my series about bioanalysis for the pharmacokineticist, I thought I would start with the…
CertaraJuly 8, 2014
What Can We Learn from Dose Normalization?
Dose normalization is a common calculation performed with pharmacokinetic parameters. The general process is to…
CertaraMay 19, 2014
Simplifying Deconvolution
Deconvolution is used to evaluate the absorption kinetics of a drug. Unfortunately the term can…
CertaraJanuary 13, 2014
Cassette Dosing: Advantages and Challenges
Cassette dosing is a technique primarily used in drug discovery efforts in non-clinical studies to…
CertaraDecember 16, 2013
What is GLP (Good Laboratory Practice)?
Good laboratory practice or GLP is a set of principles intended to assure the quality…
CertaraDecember 9, 2013
Understanding Steady State Pharmacokinetics
Register for our July 10 webinar and discover fast, flexible, frictionless PK/PD workflows with Phoenix…
CertaraNovember 25, 2013
What is Identifiability?
Developing models for pharmacokinetic or pharmacodynamic data requires creativity, patience, and hard work. Sometimes that…
CertaraNovember 18, 2013
What is the -2LL or the Log-likelihood Ratio?
Understand the 2LL (Log-likelihood Ratio) and its role in statistical analysis. Explore how it aids…
CertaraOctober 28, 2013
