Population Pharmacokinetics and Exposure-response of Osimertinib in Patients with Non-small Cell Lung Cancer Publication Population Pharmacokinetics and Exposure-response of Osimertinib in Patients with Non-small Cell Lung Cancer CertaraDecember 18, 2016
Intravenous Topiramate: Pharmacokinetics in Dogs with Naturally Occurring Epilepsy Publication Intravenous Topiramate: Pharmacokinetics in Dogs with Naturally Occurring Epilepsy CertaraDecember 5, 2016
The Pharmacokinetics of Transdermal Flunixin Meglumine in Holstein Calves Publication The Pharmacokinetics of Transdermal Flunixin Meglumine in Holstein Calves This study describes the pharmacokinetics of topical and intravenous (IV) flunixin meglumine in Holstein calves.…CertaraDecember 1, 2016
Modeling and Experimental Studies of Obeticholic Acid Exposure and the Impact of Cirrhosis Stage Publication Modeling and Experimental Studies of Obeticholic Acid Exposure and the Impact of Cirrhosis Stage CertaraDecember 1, 2016
A Randomized Dose Escalation Study of Intravenous Baclofen in Healthy Volunteers: Clinical Tolerance and Pharmacokinetics Publication A Randomized Dose Escalation Study of Intravenous Baclofen in Healthy Volunteers: Clinical Tolerance and Pharmacokinetics CertaraNovember 17, 2016
Impact of Target-mediated Elimination on the Dose and Regimen of Evolocumab, a Human Monoclonal Antibody Against Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Publication Impact of Target-mediated Elimination on the Dose and Regimen of Evolocumab, a Human Monoclonal Antibody Against Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) CertaraNovember 15, 2016
Modeling and Simulation Guides Dosing for a New Anti-psychotic Drug Blog Modeling and Simulation Guides Dosing for a New Anti-psychotic Drug Drug development is becoming more complex than ever. Regulatory agencies expect sponsors to consider a…CertaraOctober 21, 2016
Profiling the Relationship Between Tumor-associated Macrophages and Pharmacokinetics of Liposomal Agents in Preclinical Murine Models Publication Profiling the Relationship Between Tumor-associated Macrophages and Pharmacokinetics of Liposomal Agents in Preclinical Murine Models CertaraOctober 5, 2016
Gulp1 is Associated with the Pharmacokinetics of PEGylated Liposomal Doxorubicin (PLD) in Inbred Mouse Strains Publication Gulp1 is Associated with the Pharmacokinetics of PEGylated Liposomal Doxorubicin (PLD) in Inbred Mouse Strains CertaraOctober 1, 2016
Rare Disease and Orphan Drug Development Brochure Rare Disease and Orphan Drug Development There are 7,000 rare diseases impacting 350 million patients worldwide, yet only 300 of these…CertaraAugust 3, 2016