Towards Virtual Exposure Assessment of Dermally Applied Drugs – PBPK Model of Buprenorphine Transdermal Patches Poster Towards Virtual Exposure Assessment of Dermally Applied Drugs – PBPK Model of Buprenorphine Transdermal Patches CertaraAugust 29, 2019
Integration of physicochemical product characteristics within a mechanistic dermal PBPK model to support virtual bioequivalence evaluation of topical drug products: A case study with acyclovir topical creams Poster Integration of physicochemical product characteristics within a mechanistic dermal PBPK model to support virtual bioequivalence evaluation of topical drug products: A case study with acyclovir topical creams CertaraAugust 29, 2019
Formulations can have an impact on intestinal drug-drug interactions: A PBPK study using oxybutynin as a model drug Poster Formulations can have an impact on intestinal drug-drug interactions: A PBPK study using oxybutynin as a model drug CertaraAugust 29, 2019
Effect of Multiple Drugs Interacting with the hERG Channel – In Vitro Study Poster Effect of Multiple Drugs Interacting with the hERG Channel – In Vitro Study CertaraAugust 29, 2019
Performance Verification of V17 updates to Sim Japanese Population: a focus on CYP abundance Poster Performance Verification of V17 updates to Sim Japanese Population: a focus on CYP abundance CertaraAugust 29, 2019
VIVD: a Virtual In Vitro Distribution Model for Predicting Intra- and Sub-Cellular Concentrations in Toxicity Assays Poster VIVD: a Virtual In Vitro Distribution Model for Predicting Intra- and Sub-Cellular Concentrations in Toxicity Assays CertaraAugust 29, 2019
On Early Paediatric Study Design: Sample Size Calculation using a PBPK Approach within the Simcyp Simulator Poster On Early Paediatric Study Design: Sample Size Calculation using a PBPK Approach within the Simcyp Simulator CertaraAugust 29, 2019
Development and Integration of a Dynamic Lactation Functionality within a Full PBPK Model Poster Development and Integration of a Dynamic Lactation Functionality within a Full PBPK Model CertaraAugust 29, 2019
Physiologically-Based Pharmacokinetic (PBPK) Modelling Approach for the Prediction of Small Intestinal Precipitation of Poorly Soluble Drugs – A Simulation Study of Posaconazole Using the Simcyp ADAM Model Poster Physiologically-Based Pharmacokinetic (PBPK) Modelling Approach for the Prediction of Small Intestinal Precipitation of Poorly Soluble Drugs – A Simulation Study of Posaconazole Using the Simcyp ADAM Model CertaraAugust 28, 2019
In silico assessment of antiarrhythmic effects of drug ranolazine on electrical activity in human ventricular myocardium Poster In silico assessment of antiarrhythmic effects of drug ranolazine on electrical activity in human ventricular myocardium CertaraAugust 28, 2019
