Cardiac Safety Simulator
Predicts drug-induced cardiovascular risks early, enabling informed decisions and reducing costly late-stage failures.
CertaraApril 27, 2016
Recent Advances in Development and Application of Physiologically-based Pharmacokinetic (PBPK) Models: A Transition from Academic Curiosity to Regulatory Acceptance
There is a renewed surge of interest in applications of physiologically-based pharmacokinetic (PBPK) models by the…
CertaraApril 14, 2016
Inside the Mind of Pharmacometrics Pioneer, Professor Malcolm Rowland
Officially, Prof. Malcolm Rowland has retired. This scientific pioneer has been helping lay the foundation…
CertaraFebruary 23, 2016
Conventional & Mechanistic IVIVC: Complementary or Clashing Methods?
An IVIVC (in vitro-in vivo correlation) is a mathematical relationship that predicts key pharmacokinetic parameters…
CertaraFebruary 9, 2016
Modeling the Influence of Ethnicity on Drug Disposition
Ever noticed how people from different ethnic backgrounds respond differently to drugs? For example, you…
CertaraNovember 23, 2015
Interplay of Metabolism and Transport in Determining Oral Drug Absorption and Gut Wall Metabolism: A Simulation Assessment Using the “Advanced Dissolution, Absorption, Metabolism (ADAM)” Model
Bioavailability of orally administered drugs can be influenced by a number of factors including release…
CertaraNovember 1, 2015
How to Optimize Your Drug Label Using Modeling and Simulation Technology
As a trained pharmacist and scientist, I think a lot about patient care and how…
CertaraSeptember 29, 2015
100 Articles That Will Help You Understand PBPK Modeling & Simulation
As a company with a strong academic foundation, our scientists actively publish the results of…
CertaraJuly 28, 2015
How to Revamp Your Approach to Conventional IVIVC Models
An IVIVC (in vitro-in vivo correlation) is a predictive mathematical model describing the relationship between…
CertaraJuly 21, 2015
