Evaluation of Dosing Strategy for Pembrolizumab for Oncology Indications Publication Evaluation of Dosing Strategy for Pembrolizumab for Oncology Indications CertaraMay 1, 2017
CYP2C9 Genotype-dependent Warfarin Pharmacokinetics: Impact of CYP2C9 Genotype on R- and S-Warfarin and Their Oxidative Metabolites Publication CYP2C9 Genotype-dependent Warfarin Pharmacokinetics: Impact of CYP2C9 Genotype on R- and S-Warfarin and Their Oxidative Metabolites CertaraMarch 1, 2017
Population Pharmacokinetics and Exposure-response of Osimertinib in Patients with Non-small Cell Lung Cancer Publication Population Pharmacokinetics and Exposure-response of Osimertinib in Patients with Non-small Cell Lung Cancer CertaraDecember 18, 2016
Profiling the Relationship Between Tumor-associated Macrophages and Pharmacokinetics of Liposomal Agents in Preclinical Murine Models Publication Profiling the Relationship Between Tumor-associated Macrophages and Pharmacokinetics of Liposomal Agents in Preclinical Murine Models CertaraOctober 5, 2016
Gulp1 is Associated with the Pharmacokinetics of PEGylated Liposomal Doxorubicin (PLD) in Inbred Mouse Strains Publication Gulp1 is Associated with the Pharmacokinetics of PEGylated Liposomal Doxorubicin (PLD) in Inbred Mouse Strains CertaraOctober 1, 2016
Population Pharmacokinetics of Bevacizumab in Cancer Patients with External Validation Publication Population Pharmacokinetics of Bevacizumab in Cancer Patients with External Validation CertaraAugust 1, 2016
Physiologically-based Pharmacokinetic Modeling in Pediatric Oncology Drug Development Publication Physiologically-based Pharmacokinetic Modeling in Pediatric Oncology Drug Development CertaraJuly 1, 2016
Lessons Learned: Dose Selection of Small Molecule-targeted Oncology Drugs Publication Lessons Learned: Dose Selection of Small Molecule-targeted Oncology Drugs CertaraJune 1, 2016
Population Pharmacokinetic/Pharmacodynamic Modeling of Tumor Growth Kinetics in Medullary Thyroid Cancer Patients Receiving Cabozantinib Publication Population Pharmacokinetic/Pharmacodynamic Modeling of Tumor Growth Kinetics in Medullary Thyroid Cancer Patients Receiving Cabozantinib Nonlinear mixed effects models were developed to describe the relationship between cabozantinib exposure and target…CertaraApril 27, 2016
Breast Cancer Resistance Protein Abundance, but Not mRNA Expression, Correlates with Estron e-3-Sulfate Transport in Caco-2 Publication Breast Cancer Resistance Protein Abundance, but Not mRNA Expression, Correlates with Estron e-3-Sulfate Transport in Caco-2 Transporter mRNA and protein expression data are used to extrapolate in vitro transporter kinetics to in…CertaraApril 1, 2016