Bridging the Gap: Integrating Quantitative Systems Pharmacology and Pharmacometrics in Drug Development
Quantitative Systems Pharmacology (QSP) and Pharmacometrics (PMX) have historically existed at the two ends of…
CertaraJanuary 7, 2026
Evaluation of a New Formulation That Improves the Bioavailability and Food Effect of Abiraterone: An Open-Label, Crossover, Randomized, Controlled, Phase I Clinical Trial
Find out how RL001 delivers >1000 mg tablet exposure with reduced food effect and improved…
CertaraJanuary 1, 2026
Pharmacokinetics, Bioequivalence, and Safety of Diclofenac Sodium Sustained-Release Tablets in Healthy Chinese Subjects Under Fasting and Fed Conditions
Explore how two replicated trials confirm diclofenac SR test and reference tablets are bioequivalent under…
CertaraJanuary 1, 2026
A Systematic Review and Model-Based Meta-Analysis of Pegylated-Interferon-α-Induced HBsAg Loss in Chronic Hepatitis B Virus Infection
This study synthesizes data from a large body of clinical trials to evaluate rates of…
CertaraDecember 18, 2025
Accelerated ADC Approval Through Expert Modeling and Data Rescue
See how Certara rescued complex ADC PK datasets, delivered PopPK, exposure-response modeling, and enabled rapid…
CertaraDecember 15, 2025
Pharmacokinetic and bioequivalence of two formulations of Valsartan/Amlodipine Tablet(I) in healthy Chinese volunteers: A randomized, three-period, partially replicated crossover study
Discover how randomized crossover study shows new valsartan/amlodipine formulation is bioequivalent to the reference product,…
CertaraDecember 13, 2025
Merck Advances Pediatric Oncology with Innovative ADC Modeling
Merck leveraged ADC modeling and pediatric ADC dose optimization to enable FDA acceptance and advance…
CertaraDecember 12, 2025
New Approach Methodologies (NAMs): By the numbers
We outline today’s animal-use landscape, the rise of NAMs, & how the Non-Animal Navigator supports…
CertaraDecember 10, 2025
