Publication

Recent applications of pharmacometrics and systems pharmacology approaches to improve and optimize drug therapy for pregnant and lactating women

The article "Recent Applications of Pharmacometrics and Systems Pharmacology Approaches to Improve and Optimize Drug…

CertaraNovember 18, 2024

Blog

PBPK modeling to support bioequivalence & generic product approvals

Physiologically-based pharmacokinetic modeling can be used to support bioequivalence (BE) assessment of complex and locally…

CertaraNovember 12, 2024

Publication

A Sequential Population Pharmacokinetic Model of Zilovertamab Vedotin in Patients with Hematologic Malignancies Extrapolated to the Pediatric Population

CertaraNovember 7, 2024

Publication

Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a recombinant human monoclonal antibody

The article titled "Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a…

CertaraNovember 4, 2024

Conference

JSCPT 2026 in Japan

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CertaraOctober 31, 2024

Publication

Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women

The article titled "Using PBPK modeling to supplement clinical data and support the safe and…

CertaraOctober 30, 2024

Publication

Impact of Milk pH and Fat Content on the Prediction of Milk-to-Plasma Ratio

Explore how milk pH and fat content influence drug milk-to-plasma ratio predictions and inform lactation…

CertaraOctober 25, 2024

Conference

16th Annual World ADC London 2026

CertaraOctober 11, 2024

Publication

A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk

The article, authored by Caroline Sychterz, Hong Shen, Yueping Zhang, Michael Sinz, Amin Rostami-Hodjegan, Brian…

CertaraSeptember 18, 2024

Publication

A tutorial on PBPK approaches in lactation research

Learn how physiologically based pharmacokinetic modeling can support drug transfer and infant exposure predictions during…

CertaraSeptember 16, 2024

Model Informed Drug Development

Recent applications of pharmacometrics and systems pharmacology approaches to improve and optimize drug therapy for pregnant and lactating women

PBPK modeling to support bioequivalence & generic product approvals

A Sequential Population Pharmacokinetic Model of Zilovertamab Vedotin in Patients with Hematologic Malignancies Extrapolated to the Pediatric Population

Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a recombinant human monoclonal antibody

JSCPT 2026 in Japan

Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women

Impact of Milk pH and Fat Content on the Prediction of Milk-to-Plasma Ratio

16th Annual World ADC London 2026

A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk

A tutorial on PBPK approaches in lactation research

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