Mechanistic Models of COVID-19: Insights into Disease Progression, Vaccines, and Therapeutics
The COVID-19 pandemic has severely impacted health systems and economies worldwide. Significant global efforts …(cont.)
Tag: COVID-19
ScienceDirect: Effect of early treatment with metformin on risk of emergency care and hospitalization among patients with COVID-19: The TOGETHER randomized platform clinical trial
Observational studies have postulated a therapeutic role of metformin in treating COVID-19. We conducted …(cont.)
Bloomberg Podcast: Omicron Continues To Spread
Dec 02, 2021 Hosts Alix Steel and Guy Johnson speak with Opinion Columnist Marcus Ashworth, BI Director of research Sam Fazeli, European Oil Team Leader James Herron, Certara CEO William Feehery, Grab Co-Founder Hooi Ling Tan
Certara’s Simcyp™ COVID-19 Vaccine Model Wins R&D 100 Award
Biosimulation tool to conduct ‘what-if’ scenarios with virtual patients recognized in Software/Services category PRINCETON, NJ – October 25, 2021 – Certara, Inc. (Nasdaq: CERT), a global leader in biosimulation, today announced that its Simcyp COVID-19 Vaccine Model has won an R&D 100 Award, which recognizes the top 100 “R&D pioneers and their revolutionary ideas in … Continued
COVID-19 Vaccines: US Approvals Vs Authorization as of October 11, 2021
There is a lot of misinformation about whether or not the COVID-19 vaccines have “full” FDA approval or Emergency Use Authorization (EUA). The words approval and authorization are often used incorrectly; they are not interchangeable. On March 27, 2020, the Secretary of health and Human Services (HHS) issued a declaration that there is a public … Continued
How COVID-19 has fundamentally changed clinical research in global health
By: Jay J HParkMSc, RobinMoggPhD, Gerald ESmithMSc, EtheldredaNakimuli-MpunguPhD, FyezahJehanMBBS, Craig RRaynerPharmD, JeanineCondoPhD, Eric HDecloedtPhD, ProfJean BNachegaPhD, GilmarReisPhD, ProfEdward, JMillsFRCP COVID-19 has had negative repercussions on the entire global population. Despite there being a common goal that should have unified resources and efforts, there have been an overwhelmingly large number of clinical trials that have been … Continued
Australia’s current COVID-19 treatment options, and why the national fatality rate is so high
By health reporter Lauren Roberts As Australia’s vaccine rollout eases — slowly — into its second phase, experts are pausing to reflect on how far we’ve come with COVID-19 treatments and what the prospects are (…)
ISPE Pharmaceutical Engineering: Model-Informed Drug Development Addresses COVID-19 Challenges
by Patrick Smith and Karen Rowland, PhD To read the article click below.
The Landscape of Emerging Randomized Clinical Trial Evidence for COVID-19 Disease Stages: A Systematic Review of Global Trial Registries
Alison Dillman,1 Michael J Zoratti,2 Jay JH Park,3 Grace Hsu,2 Louis Dron,2 Gerald Smith,2 Ofir Harari,2 Craig R Rayner,4 Noor-E Zannat,2 Alind Gupta,2 Eric Mackay,5 Paul Arora,6 Zelyn Lee,7 Edward J Mills2 A multitude of randomized controlled trials (RCTs) have emerged in response to the novel coronavirus disease (COVID-19) pandemic. Understanding the distribution of trials among various settings is important to guide future research priorities and efforts. The … Continued
How COVID-19 Affects Stakeholder Engagement & Value Communication
By Tom Hemy The COVID-19 pandemic has made the development and commercialization of pharmaceuticals and medical devices even more challenging. For example, in the value communication and stakeholder engagement area, many field representatives found themselves refused entry to hospitals and surgeries and unable to meet in-person with payers, doctors, and other key stakeholders. These meetings … Continued