Development of a human PBMC TXG-MAPr as a mechanistic framework to interpret toxicodynamic variability across the human population Poster Development of a human PBMC TXG-MAPr as a mechanistic framework to interpret toxicodynamic variability across the human population Leiden University and EFSA researchers present the PBMC TXG-MAPr — a network-based transcriptomic tool mapping…CertaraJune 23, 2026
Characterization of human toxicodynamic variability using peripheral blood mononuclear cells from a large cohort of healthy volunteers Poster Characterization of human toxicodynamic variability using peripheral blood mononuclear cells from a large cohort of healthy volunteers Research from Leiden University and EFSA characterizing interindividual toxicodynamic variability using peripheral blood mononuclear cells…CertaraJune 23, 2026
Certara Launches Bio Venture Catalyst for Emerging Biotechs to De-risk Investment and Accelerate Development Announcement Certara Launches Bio Venture Catalyst for Emerging Biotechs to De-risk Investment and Accelerate Development Integrated offering combines drug development, regulatory, commercial, and investor strategy expertise to help early-stage biotech…Danielle PillsburyJune 23, 2026
Integrating Endogenous Ligand Competition into a Mechanistic Whole-Body PBPK Model of Therapeutic Monoclonal Antibodies Poster Integrating Endogenous Ligand Competition into a Mechanistic Whole-Body PBPK Model of Therapeutic Monoclonal Antibodies Discover how endogenous ligand competition was incorporated into a whole-body PBPK model to improve prediction…CertaraJune 23, 2026
Application of IO Simulator in Immuno-Oncology Combination Therapy: A Small Cell Lung Cancer Case Study Poster Application of IO Simulator in Immuno-Oncology Combination Therapy: A Small Cell Lung Cancer Case Study Learn how Certara's IO Simulator was used to predict efficacy, cytokine release syndrome risk, and…CertaraJune 23, 2026
Mechanistic Modelling of CRS in T-cell Engagers – An Application for Blinatumomab Poster Mechanistic Modelling of CRS in T-cell Engagers – An Application for Blinatumomab Discover how Quantitative Systems Pharmacology (QSP) was used to predict cytokine release syndrome risk and…CertaraJune 23, 2026
Machine Learning-Based Covariate Selection for Population Pharmacokinetic Modeling Poster Machine Learning-Based Covariate Selection for Population Pharmacokinetic Modeling Authors: Ibtissem Rebai (Certara), Stephen Duffull (Certara), Ayman Akil (Certara), Anna Largajolli (Certara), Floris Fauchet…CertaraJune 22, 2026
Shaping the future of AI/ML in pharmacometrics through collaboration, education and best practices Poster Shaping the future of AI/ML in pharmacometrics through collaboration, education and best practices Discover how the AI/ML Special Interest Group is advancing responsible artificial intelligence in pharmacometrics through…CertaraJune 22, 2026
Accelerating QSP Virtual Population Generation Through Active Learning and Bayesian Optimization Poster Accelerating QSP Virtual Population Generation Through Active Learning and Bayesian Optimization Discover how active learning and Bayesian optimization improve virtual population generation for quantitative systems pharmacology…CertaraJune 18, 2026
Mechanistic QSP Modeling to Support KIT Inhibitor Dose Selection, Biomarker Strategy, and Clinical Development Poster Mechanistic QSP Modeling to Support KIT Inhibitor Dose Selection, Biomarker Strategy, and Clinical Development Discover how a mechanistic quantitative systems pharmacology (QSP) model predicts mast cell inhibition and depletion…CertaraJune 16, 2026