The Absorption Kinetics of Ketoconazole Plays a Major Role in Explaining the Reported Variability in the Level of Interaction with Midazolam: Interplay Between Formulation and Inhibition of Gut Wall and Liver Metabolism Publication
Application of the MechPeff Model to Predict Passive Effective Intestinal Permeability in the Different Regions of the Rodent Small Intestine and Colon Publication
Prediction of Liver Volume—A Population-based Approach to Meta-analysis of Pediatric, Adult, and Geriatric Populations—An Update Publication
Biopharmaceutics Data Management System for Anonymized Data Sharing and Curation: First Application with Orbito IMI Project Publication
Optimization of Intestinal Microsomal Preparation in the Rat: A Systematic Approach to Assess the Influence of Various Methodologies on Metabolic Activity and Scaling Factors Publication
Early Assessment of Proarrhythmic Risk of Drugs Using the In Vitro Data and Single-cell-based In Silico Models: Proof of Concept Publication
Towards a Best Practice Approach in PBPK Modeling: Case Example of Developing a Unified Efavirenz Model Accounting for Induction of CYPs 3A4 and 2B6 Publication
Metformin and Cimetidine: Physiologically-based Pharmacokinetic Modeling to Investigate Transporter Mediated Drug–drug Interactions Publication
Drug-drug Interactions and QT Prolongation as a Commonly Assessed Cardiac Effect—Comprehensive Overview of Clinical Trials Publication