The Determination of Drug Metabolizing Enzyme Activity In Vivo: Pharmacokinetics and Statistical Issues Publication The Determination of Drug Metabolizing Enzyme Activity In Vivo: Pharmacokinetics and Statistical Issues Probe substrates for various isoforms of cytochrome P450 and other drug-metabolizing enzymes are now widely…CertaraDecember 1, 1998
Caffeine Metabolic Ratios as Markers of Enzyme Activity: A Theoretical Assessment Publication Caffeine Metabolic Ratios as Markers of Enzyme Activity: A Theoretical Assessment At least six urinary metabolite ratios of caffeine have been proposed as probes for in…CertaraApril 1, 1996
The future of Parkinson’s disease research: A new paradigm of human-specific investigation is necessary… and possible Publication The future of Parkinson’s disease research: A new paradigm of human-specific investigation is necessary… and possible Parkinson’s disease (PD) is a complex neurodegenerative condition with a multifactorial origin. To date, approaches…CertaraApril 8, 0202