Commentary on “In Silico Modeling of Gastrointestinal Drug Absorption: Predictive Performance of Three Physiologically-based Absorption Models” Publication Commentary on “In Silico Modeling of Gastrointestinal Drug Absorption: Predictive Performance of Three Physiologically-based Absorption Models” CertaraJanuary 1, 2017
Population Pharmacokinetics and Exposure-response of Osimertinib in Patients with Non-small Cell Lung Cancer Publication Population Pharmacokinetics and Exposure-response of Osimertinib in Patients with Non-small Cell Lung Cancer CertaraDecember 18, 2016
Intravenous Topiramate: Pharmacokinetics in Dogs with Naturally Occurring Epilepsy Publication Intravenous Topiramate: Pharmacokinetics in Dogs with Naturally Occurring Epilepsy CertaraDecember 5, 2016
The Pharmacokinetics of Transdermal Flunixin Meglumine in Holstein Calves Publication The Pharmacokinetics of Transdermal Flunixin Meglumine in Holstein Calves This study describes the pharmacokinetics of topical and intravenous (IV) flunixin meglumine in Holstein calves.…CertaraDecember 1, 2016
Limitations of MIC as Sole Metric of Pharmacodynamic Response Across the Range of Antimicrobial Susceptibilities within a Single Bacterial Species Publication Limitations of MIC as Sole Metric of Pharmacodynamic Response Across the Range of Antimicrobial Susceptibilities within a Single Bacterial Species The minimum inhibitory concentration (MIC) of an antimicrobial drug for a bacterial pathogen is used…CertaraDecember 1, 2016
Modeling and Experimental Studies of Obeticholic Acid Exposure and the Impact of Cirrhosis Stage Publication Modeling and Experimental Studies of Obeticholic Acid Exposure and the Impact of Cirrhosis Stage CertaraDecember 1, 2016
Quantifying Gut Wall Metabolism: Methodology Matters Publication Quantifying Gut Wall Metabolism: Methodology Matters CertaraDecember 1, 2016
Pharmacokinetics of Oral Terbinafine in Adult Horses Publication Pharmacokinetics of Oral Terbinafine in Adult Horses The primary study objective was to compare the pharmacokinetics of p.o. terbinafine alone to p.o.…CertaraNovember 24, 2016
Vaccination Mitigates the Impact of PRRSv Infection on the Pharmacokinetics of Ceftiofur Crystalline-free Acid in Pigs Publication Vaccination Mitigates the Impact of PRRSv Infection on the Pharmacokinetics of Ceftiofur Crystalline-free Acid in Pigs The pharmacokinetics of intramuscularly administered ceftiofur crystalline-free acid (CCFA) were determined in pigs that were…CertaraNovember 24, 2016
Early Assessment of Proarrhythmic Risk of Drugs Using the In Vitro Data and Single-cell-based In Silico Models: Proof of Concept Publication Early Assessment of Proarrhythmic Risk of Drugs Using the In Vitro Data and Single-cell-based In Silico Models: Proof of Concept CertaraNovember 23, 2016