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Conference: Alzheimer’s Association International Conference (AAIC®)

Date: July 27 - 31, 2025

Location: Toronto, Canada

Booth:

Join Certara at the Alzheimer’s Association International Conference (AAIC®)

We’re excited to participate in AAIC 2025—the world’s largest gathering of researchers, clinicians, and professionals dedicated to Alzheimer’s and dementia science.

Featured Presentation

Wednesday, July 30, 12:30 PM – 1:45 PM
QSP Analysis of Inhibition of Amyloid Oligomer Formation by Valiltramiprosate

Presenter: Hugo Geerts, PhD, Senior Principal Scientist, Certara
A pioneer in QSP modeling with over 20 years of experience advancing neuroscience innovation

What You’ll Learn:

  • The role of the APOE4 genotype in Alzheimer’s disease progression through QSP modeling
  • How amyloid-beta aggregation dynamics contribute to neurodegeneration and hippocampal atrophy
  • The impact of Valiltramiprosate on disease trajectory, including effects on amyloid aggregation and brain volume loss

Additional Highlights

Hugo will also present two abstracts that address a growing priority in neuroscience R&D: ensuring the right treatment reaches the right patient at the right time. His team’s research highlights how model-informed strategies can:

  • Account for patient variability (e.g., APOE genotype, disease stage)
  • Enable smarter, more targeted clinical trial designs
  • Reduce trial failure and accelerate development timelines
  • Support early intervention without increasing patient risk

These insights are shaping the future of personalized Alzheimer’s treatment.

Connect with Hugo Geerts and Sophia Marshall, Associate Director, at AAIC 2025.

Explore how Certara’s QSP expertise is unlocking new frontiers in neurodegenerative drug development.