PK/PD Modeling & Simulation

How Can PK/PD Analysis Add Value to Patient Care?

Nathan Teuscher

In May 2011, T.J. Smith and B.E. Hillner published an opinion piece in the New England Journal of Medicine titled “Bending the Cost Curve in Cancer Care” (link). In this opinion piece, Smith and Hillner suggest that the rapidly increasing cost of treating cancer is not sustainable. “We must find ways to reduce the costs […]

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Topics: PK/PD Modeling & Simulation

What is Curve Stripping?

Nathan Teuscher

The process of curve stripping is used in both compartmental and non-compartmental analysis. Each pharmacokinetic profile is made up of one or more exponential phases. The “curve stripping” process extracts each of these exponential phases from the pharmacokinetic profile in a manual fashion that does not require non-linear curve fitting. This method was originally used […]

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Topics: PK/PD Modeling & Simulation
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