May 2011

Publication

Mechanistic PKPD models are now advocated not only by academic and industrial researchers, but also…

CertaraMay 11, 2011

Publication

In drug development, clinical medicine, or health policy making, basing one's decisions on a selective…

CertaraMay 1, 2011

Publication

UDP-glucuronosyltransferases (UGTs) are critical for the metabolism and clearance of drugs, chemicals, and hormones. The…

CertaraMay 1, 2011

Publication

It is imperative that new drugs demonstrate adequate pharmacokinetic properties, allowing an optimal safety margin…

CertaraMay 1, 2011

Publication

Clofarabine, a newer purine analog with reduced central nervous system toxicity, may prove advantageous in…

CertaraMay 1, 2011