Software

Certara offers predictive science and informatics solutions that enable cross-disciplinary and translational approaches to drug development.

PK/PD Modeling and Simulation

Autopilot Features Tour

Learn about key features that enable PK automation

AutoPilot Object in Phoenix workflow

Just by adding one or multiple AutoPilot objects to the project's workflow and by connecting it to the results of NCA objects, a user can generate a multitude of standard tables and graphs that are required for regulatory or interim reporting.

Extensive User Control

The User Interface of the AutoPilot object provides the user with extensive control over the generated tables and graphs. Of course, this control is limited by the settings provided by the company's AutoPilot administrator, who sets the boundaries using the Administration Module, so that corporate report policies and requirements are met.

Integrated File Explorer

An easy to use tool - accessible in the Reporting tab of the AutoPilot object - helps to browse through the generated output and to transfer selected tables and graphs into a Word document or a PowerPoint presentation.

PK Output integrated in Phoenix Project

Because the generated tables and graphs are stores as results of the AutoPilot object, all relevant data are together in the Phoenix project: study data, NCA analysis, and PK tables and graphs.

Administration Module

The Administration Module allows customers to configure AutoPilot with respect to business rules and output content and formatting. The settings are stored in files that can be shared across an organization, so that corporate policies and reporting requirements are easily implemented.

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AutoPilot Toolkit™ for Phoenix®

Integrated PK Automation For Increased Productivity and Quality

AutoPilot Toolkit for Phoenix is a configurable PK Automation software package that is integrated with Phoenix WinNonlin, the industry standard for Non-Compartmental Analysis (NCA) and PK / PD modeling. AutoPilot Toolkit generates report-quality tables and figures for regulatory submissions and interim reports and presentations. As part of the Phoenix workflow, it operates on study data and NCA results in a Phoenix project from the user’s file system or from the controlled PK/PD data repository based on Pharsight Knowledgebase Server™ (PKS™).

AutoPilot Toolkit for Phoenix automates the production of tables and figures based on study data and NCA results created through Phoenix WinNonlin. Typical PK studies that are supported by AutoPilot Toolkit include IV- or PO-based non-compartmental analysis and inferential statistics (e.g., bioequivalence testing) as well as comparisons between analytes, dosing regimen, or other conditions. Study datasets can be organized as stacked or wide data. Examples of common study design types that AutoPilot supports include:

  • Bioequivalence and Bioavailability
  • Drug-Drug and Food-Drug interactions
  • First-in-man
  • Dose Proportionality
  • Special Populations (e.g. renal, hepatic, age)

Key Benefits

  • Reduce the cycle time to complete interim and final PK reports by up to 75%
  • Improve quality of reports leading to reduced effort in QA and Regulatory Affairs groups
  • Capture and implement best practices and business rules within a department and across organizations
  • Enable PK scientists to focus their time on rewarding and critical drug development research