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Physiologically-based Pharmacokinetics Modeling: An Approach for Designing Better Clinical Trials

20160426
On-Demand Webinar
YouTube video

In this webinar, Dr. Marylore Chenel, director of Pharmacometrics at Servier, discussed how PBPK modeling is a tool that can help sponsors design better clinical studies. She illustrated this approach using two case studies. The first case study demonstrated how to evaluate potential drug-drug interactions (DDIs) with PBPK models and design multi-response sampling strategies using the example of midazolam and a phase I compound. The second case study covered designing pediatric clinical trials using PBPK and optimal design methods.