A Student’s Perspective on Using Phoenix NLME for PopPK Analysis of an Intranasal Combination Drug

The pharmacokinetic dispositions and the underlying variability of Kovacaine Mist®, a combination product containing oxymetazoline and tetracaine, were investigated by nonlinear mixed effects modeling using Phoenix® NLME. The project utilized the different plugins in the Phoenix® platform allowing all steps of model development right from data setup to producing publication quality graphs in a single seamless environment. This webinar presented a student’s journey through his introduction to Phoenix NLME and how it became his primary tool for population modeling.