Virtual Populations

Virtual Populations

Virtual Populations in the Simcyp Simulator The utility of in vitro-in vivo extrapolation has historically been limited by: Projections are usually only made to mean data collected in studies in healthy, young, Caucasian, male individuals. Other approaches provide inadequate estimates of intersubject variability based solely on simple demographic parameters. This limits their ability to address the […]

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Simcyp Animal

A PBPK Modeling Platform for Veterinary and Pre-clinical Drug Research Simcyp® Animal is a whole-body physiologically-based pharmacokinetic (PBPK) modeling platform for rat, dog, and knock-out mouse. It is based on the Simcyp Simulator with simplified interfaces and well-validated models. Simulations with Simcyp Animal can help identify key data requirements and inform the design of subsequent […]

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Simcyp Simulator

The Standard for Population-based Pharmacokinetic Modeling and Simulation Used by all of the top 10 global pharmaceutical companies, together with the US Food and Drug Administration (FDA) and other key regulatory agencies, the Simcyp® Simulator is the industry’s most sophisticated solution for assisting in dose selection and informing product labeling. It links in vitro data […]

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