Simulating Viral Dynamics in the New Trial Simulator

Suzanne Minton, Bill Poland

Antiviral drug development presents a unique set of challenges. First, viruses are constantly mutating, and drug-resistant viruses emerge easily. Therefore, combination therapies are typically required to maintain a sustained virologic response. In addition, successful treatment requires high medication adherence, which is often a challenge for patients with chronic viral infections such as hepatitis or HIV. […]

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Topics: PK/PD Modeling & Simulation

Phoenix Modeling Language School

Learn How to Build Custom PK and PK/PD Models Phoenix WinNonlin™ uses Phoenix Modeling Language (PML) to encode pharmacokinetic (PK) and Pharmacodynamic (PD) models. Although most models can be built using the graphical user interface (GUI) in Phoenix, there are some models that require custom coding with PML. Certara has launched a series of interactive educational […]

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