PBPK Modeling & Simulation

Personalized Toxicology: A New Paradigm for Chemical Risk Assessment

Masoud Jamei

Historically, toxicity testing has been conducted by giving lab animals high doses of chemicals and observing them for adverse events. But quantifying the risks chemicals pose to humans based on animal studies is problematic as the chemical doses are often orders of magnitude higher than environmental levels. Moreover, this process is slow, expensive, and ethically […]

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Topics: PBPK Modeling & Simulation
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