PK/PD Modeling & Simulation

Modeling Delayed Outcomes in PK/PD Studies Using DDEs

Shuhua Hu

Delays are ubiquitous in pharmacokinetics (PK) and pharmacodynamics (PD) studies. Transit compartment models, described by systems of ordinary differential equations, have been widely used to describe delayed outcomes in PK and PD studies. The obvious disadvantage for this type of model is it requires manually finding proper values for the number of compartments. In addition, […]

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Topics: PK/PD Modeling & Simulation
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