Simulating Viral Dynamics in the New Trial Simulator

Suzanne Minton, Bill Poland

Antiviral drug development presents a unique set of challenges. First, viruses are constantly mutating, and drug-resistant viruses emerge easily. Therefore, combination therapies are typically required to maintain a sustained virologic response. In addition, successful treatment requires high medication adherence, which is often a challenge for patients with chronic viral infections such as hepatitis or HIV. […]

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Topics: PK/PD Modeling & Simulation