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All preclinical resources

Dose Correction for the Michaelis-Menten Approximation of the Target—Mediated Drug Disposition Model

Model Informed Drug Development, pre-update, Publication

Pharmacokinetic/Pharmacodynamic Modeling of Methylprednisolone Effects on iNOS mRNA Expression and Nitric Oxide During LPS-induced Inflammation in Rats

Model Informed Drug Development, pre-update, Publication

Physiologically-based Pharmacokinetics Joined with In Vitro-In Vivo Extrapolation of ADME: A Marriage Under the Arch of Systems Pharmacology

Model Informed Drug Development, pre-update, Publication

A Mechanistic Pharmacokinetic Model to Assess Modified Oral Drug Bioavailability Post Bariatric Surgery in Morbidly Obese Patients: Interplay Between CYP3A Gut Wall Metabolism, Permeability, and Dissolution

Model Informed Drug Development, pre-update, Publication

Pharmacokinetics, Lymph Node Uptake and Mechanistic PK Model of Near Infrared Dye Labeled Bevacizumab After IV and SC Administration in Mice

Modeling and Simulation - PK/PD, pre-update, Publication

Prediction of Drug Clearance in a Smoking Population: Modeling the Impact of Variable Cigarette Consumption on the Induction of CYP1A2

Model Informed Drug Development, pre-update, Publication

Target-mediated Pharmacokinetic and Pharmacodynamic Model of Exendin-4 in Rats, Monkeys, and Humans

Modeling and Simulation - PK/PD, pre-update, Publication

Noninvasive Real-time Fluorescence Imaging of the Lymphatic Uptake of BSA-IRDye 680 Conjugate Administered Subcutaneously in Mice

Model Informed Drug Development, pre-update, Publication

PEGylation of a Factor VIII-phosphatidylinositol Complex: Pharmacokinetics and Immunogenicity in Hemophilia A Mice

Model Informed Drug Development, pre-update, Publication

Screening of Chemicals for Human Bioaccumulative Potential with a Physiologically-based Toxicokinetic Model

Model Informed Drug Development, pre-update, Publication

From Pre-clinical to Human—Prediction of Oral Absorption and Drug-drug Interaction Potential Using Physiologically-based Pharmacokinetic (PBPK) Modeling Approach in an Industrial Setting: A Workflow by Using Case Example

Certara Products - Simcyp, Modeling and Simulation - PBPK, pre-update, Publication

Use of a Multistaged Time-dependent Inhibition Assay to Assess the Impact of Intestinal Metabolism on Drug-drug Interaction Potential

Model Informed Drug Development, pre-update, Publication
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