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All Preclinical resources

Pharmacokinetics of Dibutylphthalate in Pregnant Rats

Modeling and Simulation - PK/PD, pre-update, Publication

Assessment of In Vivo CYP2D6 Activity: Differential Sensitivity of Commonly Used Probes to Urine pH

Model Informed Drug Development, pre-update, Publication

Predicting the Clearance of CYP2C9 Substrates

Model Informed Drug Development, pre-update, Publication

Cytochrome P450 3A Expression and Activity in the Human Small Intestine

Model Informed Drug Development, pre-update, Publication

Pharmacogenetics—Expectations and Reality

Model Informed Drug Development, pre-update, Publication

Prediction of Clearance from Recombinantly Expressed CYPs: Intersystem Extrapolation Factor (ISEF)

Model Informed Drug Development, pre-update, Publication

The Effects of Dose Staggering on Metabolic Drug-drug Interactions

Model Informed Drug Development, pre-update, Publication

In Vivo Indices of Enzyme Activity—The Effect of Renal Impairment on the Assessment of CYP2D6 Activity

Model Informed Drug Development, pre-update, Publication

The Determination of Drug Metabolizing Enzyme Activity In Vivo: Pharmacokinetics and Statistical Issues

Model Informed Drug Development, pre-update, Publication

Caffeine Metabolic Ratios as Markers of Enzyme Activity: A Theoretical Assessment

Model Informed Drug Development, pre-update, Publication

The future of Parkinson’s disease research: A new paradigm of human-specific investigation is necessary… and possible

Modeling and Simulation - QSP, Publication
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