Forging the next frontier with QSP
The Certara Quantitative Systems Pharmacology (QSP) group is a global organization focused on the impactful application of QSP and mechanistic PKPD modeling and simulation in drug discovery and development.
We are leading several first-of-its-kind QSP Consortia with more than 10 global pharmaceutical companies and have a rapidly expanding consultancy portfolio. Our QSP scientists work in close collaboration with other Certara staff and clients to generate and use state-of-the-art mechanistic models for decision making in pharmaceutical R&D.
We are seeking highly motivated and talented QSP modelling experts at all levels, who share our passion for using quantitative approaches to understand and impact complex drug discovery and development questions. Positions are available at various levels of experience across our global locations and for flexible, home-based roles.
QSP Research Associate
Our QSP scientists work in close collaboration with other staff and clients to generate and use state-of-the-art mechanistic models for decision making in pharmaceutical R&D. The models are designed in close dialogue with clients and developed with a view to creating user-friendly tools that will inform drug development programs from discovery to regulatory filing. For this role, you should have postdoctoral experience in systems modelling for drug discovery/ development teams and PhD (or equivalent) in life sciences, engineering, computer sciences, mathematics, physics or equivalent. It is also essential that you have solid understanding of PKPD, pharmacology and biology and its application in drug discovery and development.
Quantitative Systems Pharmacology Positions (All Levels)
We are seeking highly motivated and talented QSP modelling experts at all levels, who share our passion for using quantitative approaches to understand and impact complex drug discovery and development questions. Besides our well-established leadership in applied QSP approaches in Immunology and Immuno-Oncology, we are now also the leading provider of QSP approaches in neuro-degenerative diseases through Certara’s recent acquisition of the In Silico Biosciences modelling platform.
Piet van der Graaf is Senior Vice President and Head of Quantitative Systems Pharmacology at Certara and Professor of Systems Pharmacology at Leiden University. From 2013-2016 he was the Director of Research of the Leiden Academic Centre for Drug Research. From 1999-2013 he held various leadership positions at Pfizer in Discovery Biology, Pharmacokinetics and Drug Metabolism and Clinical Pharmacology. He was the founding Editor-in-Chief of CPT: Pharmacometrics & Systems Pharmacology from 2012-2018 before becoming Editor-in-Chief of Clinical Pharmacology & Therapeutics. Piet received his doctorate training in clinical medicine with Nobel prize laureate Sir James Black at King’s College London. He has been awarded the 2024 Gary Neil Prize for Innovation in Drug Development from the American Society of Clinical Pharmacology and Therapeutics (ASCPT) and was the recipient of the 2021 Leadership Award from the International Society of Pharmacometrics (ISoP). Piet is an elected Fellow of the British Pharmacological Society and has published >200 articles in the area of quantitative pharmacology and drug development.
With 25 years of experience in computational biology. Andrzej has published models and software for analysis of molecular network dynamics and constraint based modelling of genome scale metabolic networks. Currently, his scientific work focuses on immuno-oncology and immunogenicity. He is a visiting Professor of Systems Biology at Surrey.
Piet van der Graaf is Senior Vice President and Head of Quantitative Systems Pharmacology at Certara and Professor of Systems Pharmacology at Leiden University. From 2013-2016 he was the Director of Research of the Leiden Academic Centre for Drug Research. From 1999-2013 he held various leadership positions at Pfizer in Discovery Biology, Pharmacokinetics and Drug Metabolism and Clinical Pharmacology. He was the founding Editor-in-Chief of CPT: Pharmacometrics & Systems Pharmacology from 2012-2018 before becoming Editor-in-Chief of Clinical Pharmacology & Therapeutics. Piet received his doctorate training in clinical medicine with Nobel prize laureate Sir James Black at King’s College London. He has been awarded the 2024 Gary Neil Prize for Innovation in Drug Development from the American Society of Clinical Pharmacology and Therapeutics (ASCPT) and was the recipient of the 2021 Leadership Award from the International Society of Pharmacometrics (ISoP). Piet is an elected Fellow of the British Pharmacological Society and has published >200 articles in the area of quantitative pharmacology and drug development.
With 25 years of experience in computational biology. Andrzej has published models and software for analysis of molecular network dynamics and constraint based modelling of genome scale metabolic networks. Currently, his scientific work focuses on immuno-oncology and immunogenicity. He is a visiting Professor of Systems Biology at Surrey.