CoMSIA Study on Substituted Aryl Alkanoic Acid Analogs as GPR40 Agonists

GPR40, a G-protein-coupled receptor has been well established to play a crucial role in regulating blood glucose levels. Hence, GPR40 is a potential target for future antidiabetic agents. The present 3D QSAR study is aimed at delineating structural parameters governing GPR40 agonistic activity.

Author(s):

Year: