Physiologically-Based Pharmacokinetic (PBPK) Modelling Approach for the Prediction of Small Intestinal Precipitation of Poorly Soluble Drugs – A Simulation Study of Posaconazole Using the Simcyp ADAM Model

Author(s): Shriram M. Pathak, Bart Hens, Amitava Mitra, Nikunj Patel, Bo Liu, Masoud Jamei, Joachim Brouwers, Patrick Augustijns, David B. Turner

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