P-gp Efflux Has No Impact on Dose Proportionality of Digoxin Bioavailability Over A Dose Range of 0.125 To 1.5 Mg: The Outcome of A New PBPK Model, That Includes the In Vitro Transporter Information, is Consistent With the Clinical Observations

Author(s): S. Neuhoff, K. Rowland-Yeo, M. Jamei, A. Rostami-Hodjegan

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