Dosing corrected for species differences in toxicokinetics using PBPK modelling predicts equivalent reactive metabolite burden following acetaminophen overdose

Author(s): Dennis Reddyhoff, Rowena Sison-Young, Lucia Livoti, Guy Vermeil De Conchard, Yannick Parmentier, Richard Weaver, Kevin Park, Ciarán Fisher, Iain Gardner, Ian Copple
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