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Physiologically-based Pharmacokinetics Modeling: An Approach for Designing Better Clinical Trials

On-Demand Webinar

In this webinar, Dr. Marylore Chenel, director of Pharmacometrics at Servier, discussed how PBPK modeling is a tool that can help sponsors design better clinical studies. She illustrated this approach using two case studies. The first case study demonstrated how to evaluate potential drug-drug interactions (DDIs) with PBPK models and design multi-response sampling strategies using the example of midazolam and a phase I compound. The second case study covered designing pediatric clinical trials using PBPK and optimal design methods.

In this webinar, Dr. Marylore Chenel, director of Pharmacometrics at Servier, discussed how PBPK modeling is a tool that can help sponsors design better clinical studies. She illustrated this approach using two case studies. The first case study demonstrated how to evaluate potential drug-drug interactions (DDIs) with PBPK models and design multi-response sampling strategies using the example of midazolam and a phase I compound. The second case study covered designing pediatric clinical trials using PBPK and optimal design methods.