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CPT: Pharmacometrics & Systems Pharmacology – Certara Leading the Way in Maternal and Infant Health!

We’re pleased to share that eight Certara scientists contributed to seven innovative articles, making up 35% of the November edition of CPT: Pharmacometrics & Systems Pharmacology.

These impactful studies demonstrate how pharmacometric and systems pharmacology approaches are transforming drug development for pregnant and lactating women and underscore

Certara’s scientific and thought leadership.

Meet the contributors:

  1. Karen Rowland Yeo
  2. Paola Coppola
  3. Eva Gil Berglund
  4. Amin Rostami Hodgen
  5. Lisa Almond
  6. Xian Pan
  7. Amita Pansari
  8. Krithika Shetty

Featured Research Highlights:

  1. Editorial – Recent applications of pharmacometrics and systems pharmacology approaches to improve and optimize drug therapy for pregnant and lactating women | Certara Author(s): Priya Jayachandran, Jane Knöchel, Brian Cicali, Karen Rowland Yeo
  2. Perspective: Medicines in pregnancy: A clinical pharmacology extrapolation framework to address knowledge gaps | Certara Author(s): Paola Coppola, Eva Gil Berglund, Karen Rowland Yeo
  3. Tutorial: A tutorial on physiologically based pharmacokinetic approaches in lactation research | Certara Author(s): Amita Pansari, Xian Pan, Lisa M. Almond, Karen Rowland-Yeo
  4. Review: https://www.certara.com/publication/a-close-examination-of-bcrps-role-in-lactation-and-methods-for-predicting-drug-distribution-into-milk/ Author(s): Caroline Sychterz, Hong Shen, Yueping Zhang, Michael Sinz, Amin Rostami-Hodjegan, Brian J. Schmidt, Lu Gaohua, Aleksandra Galetin
  5. Systematic Review: A literature review of drug transport mechanisms during lactation | Certara Author(s): Christine Gong, Lynn N. Bertagnolli, David W. Boulton, Paola Coppola
  6. Article: https://www.certara.com/publication/using-pbpk-modeling-to-supplement-clinical-data-and-support-the-safe-and-effective-use-of-dolutegravir-in-pregnant-and-lactating-women/ Author(s): Jia Ning, Amita Pansari, Karen Rowland Yeo, Aki T. Heikkinen, Catriona Waitt, Lisa M. Almond
  7. Article: Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a recombinant human monoclonal antibody | Certara Author(s): Courtney Moc Willeford, Krithika Shetty, Douglas Sheridan, Frank Engler

To view the entire November edition of CPT visit CPT: Pharmacometrics & Systems Pharmacology: Vol 13, No 11