CoMFA and CoMSIA studies on fluorinated hexahydropyrimidine derivatives

D-QSAR models of a series of fluorinated hexahydropyrimidine derivatives with cytotoxic activities have been developed using CoMFA and CoMSIA. These models provide a better understanding of the mechanism of action and structure-activity relationship of these compounds.

 

Adeayo O. Ajala, Cosmas O. Okoro
December 15, 2011
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