Predictive Performance of Caffeine Preterm PBPK Model and Effect of Time-Varying Physiology on Predictions
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Authors: Trevor Johnson
Prediction of Drug-Drug Interaction between Phenobarbital and Theophylline in Children using Physiologically-Based Pharmacokinetic Modelling
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Application of Feto-Placental-Maternal Physiologically-based Pharmacokinetic Model to Predict Tenofovir Concentration during Pregnancy
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Predictive performance of Pregnancy Physiologically based Pharmacokinetic (PBPK) model for Cefazolin in Pregnant and Non-Pregnant Women
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Application of Physiologically Based Pharmacokinetic G Modelling to Predict Ibuprofen Pharmacokinetics in _ Preterm Neonates Simcy
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Application of Physiologically Based Pharmacokinetic (PBPK) Modelling to Predict the Pharmacokinetics of Alfentanil and Midazolam in Preterm Neonates
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Revision of CYP2D6 Activity During Pregnancy in the Simcyp Pregnancy PBPK Model
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A Novel Approach to Predict Glomerular Filtration Rate from Pre-birth to Geriatrics
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On Early Paediatric Study Design: Sample Size Calculation using a PBPK Approach within the Simcyp Simulator
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Development and Integration of a Dynamic Lactation Functionality within a Full PBPK Model
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Mechanistic modelling of dermal drug absorption using the Simcyp Multi-phase Multi-layer MechDermA model: Case study of a transdermal patch formulation of weak base drug timolol
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Prediction of Prothrombin Time after Oral Administration of S-Warfarin in Different CYP2C9 Phenotypes in Asian and Caucasian populations using the Simcyp Simulator
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Prediction of Midazolam Pharmacokinetics in Pregnant Women with Coeliac Disease using Simcyp Pregnancy PBPK Model
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Prediction of Midazolam Concentration Profile in Obese Adolescent Population Using Physiologically Based Pharmacokinetic model
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Prediction of Enfuvertide Concentration-Time Profile in a Paediatric Population after Parenteral Administration Using a Physiologically Based Pharmacokinetic Model
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What Sample Size to Use When Designing Paediatric Pharmacokinetic Studies? A Critical Analysis of “Precision Criteria”
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Impact of Free Fatty Acids on Prediction of Unbound Fraction of Cefazolin and Diazepam in Plasma of Full-term Neonates
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Application of Feto-maternal Physiologically-based Pharmacokinetic Model to Predict Emtricitabine Concentration During Pregnancy
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Application of Physiologically-based Pharmacokinetic Modeling to Predict Caffeine Pharmacokinetics in a Preterm Neonatal Population
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Prediction of the Impact of Pregnancy on Sotaolol Pharmacokinetics Using the Simcyp Pregnancy PBPK Model
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