Acute toxicity and n-octanol/water partition coefficients of substituted thiophenols: Determination and QSAR analysis

The acute toxicity (-log EC50) to Photobacterium phosphoreum and the n-octanol/water partition coefficient (log Kow) of 31 kinds of substituted thiophenols were determined at 298.15K. The -log EC50 values of studied chemicals are between 4.26 and 5.89. Their log Kow values are between 1.34 and 4.02. Comparative molecular field (CoMFA) and comparative molecular similarity index […]

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